CONTRIBUTOR(S): Vetstream Ltd, Gigi Davidson, Fear Free,
Medication: Tacrolimus
Medication: Tacrolimus
Your dog has been prescribed tacrolimus ophthalmic ointment or solution for the treatment of dry eye (keratoconjunctivitis sicca) or chronic superficial keratitis.
Occasionally the topical ointment or cream version of this medication may be used to treat other disorders such as perianal fistula, atopic dermatitis, discoid lupus erythematosus and vasculitis, but topical ointments and creams should not be used in the eye.
Key points:
• For topical use only in the eye or on the skin. Do not give by mouth.
• Safety Is not established in pregnant or lactating bitches.
• Pregnant women should not handle tacrolimus.
• This is not a licensed veterinary product. Your veterinarian will explain about off-license use of medications.
• Dosage: usually twice daily – your veterinarian will advise.
This information sheet is designed to help answer commonly asked questions and help you give the medication safely and effectively to your pet. It does not contain all available information for this medication. If you have other questions or need more information, contact your veterinarian or pharmacist. Always follow the dosing instructions provided by your veterinarian.
Name, Brand names, Class of medication and Storage
Name
- Tacrolimus (ta-cro-lee-muss).
Brand name
- There are no licensed veterinary products containing tacrolimus in the UK, Europe or the US. Your veterinarian may prescribe a human medication containing this drug or a pharmacist may have to manufacture this drug for your pet. Your veterinarian can explain off-license use of medications to you.
- Protopic® Topical Ointment (0.03% and 0.1%) for skin use (human drug).
Class of medication
- Topical immunosuppressant agent and anti-inflammatory.
Storage
- Store at room temperature.
- Do not refrigerate or freeze.
- Protect from sunlight.
Why has my dog been prescribed tacrolimus?
Your veterinarian has prescribed tacrolimus for the treatment of dry eye (keratoconjunctivitis sicca) or chronic superficial keratitis.
Occasionally this medication may be used to treat other disorders such as perianal fistula, atopic dermatitis, discoid lupus erythematosus and vasculitis.
How is the medication given?
Tacrolimus ointment or liquid is applied to the affected eye (or skin). Do not use products intended for use on the skin in the eye. It is usually applied twice daily but your veterinarian will advise as to dosing regimen.
If also applying other medications to the eye, leave at least 5 minutes between applying different products.
When treating the eye, wipe away any excess medication using a clean cloth. Caregivers should wash hands after handling tacrolimus.
Are there any side-effects or drug interactions?
Side-effects are uncommon but may include irritation to the eye and surrounding skin. Let your veterinarian know if this happens.
Overdose may result in more serious side-effects. Contact your veterinarian if you have any concerns.
How long will my dog need to receive this medication?
For dry eye and other eye conditions, your dog will need to receive this medication for the rest of its life. For skin conditions, your veterinarian will advise as to how long your pet may need to be on this medication.
How should I dispose of this medication if I don’t use it all?
Dispose of any unused tacrolimus safely – do not flush down the toilet or sink. Ask your veterinary team if they take back medication for disposal. Do not save tacrolimus for future use or give to other pets.
What if I miss a dose or give an extra dose?
If you miss a dose, give the dose as soon as possible but do not give a double dose. Make sure the dose given does not exceed the total recommended dose in any 24-hour period.
My dog is unwell, should I still give the drug?
If your pet is unwell, contact your veterinarian for advice.
What should I do if this medication is accidentally given to another pet or taken by a human?
Tacrolimus should only be given to the dog that it has been prescribed for. If accidentally given to other pets, contact your veterinarian for advice.
If accidentally consumed by a human, speak to your primary care physician or poison control center.
Pregnant women should not handle this product.
Will my dog need to be monitored while on tacrolimus?
Your veterinarian may need to monitor your dog’s tear production and eye health whilst on this medication.
Further information
If you have any concerns, further information on tacrolimus can be found on the package insert or by contacting your veterinarian.
Europe & UK
- There are no licensed veterinary products containing this drug in the UK or Europe. Your veterinary surgeon may prescribe a human medication containing this drug and will explain off-license use of medications to you.
US
- There are no licensed veterinary products containing this drug in the US. Your veterinarian may prescribe a human medication containing this drug and will explain off-license use of medications to you.
Always follow the recommended dosage and contact your veterinary team or pharmacist if you have any questions regarding your dog’s medication.